Antiflatulent drugs
Antiflatulent drugs
Antiflatulents disperse gas pockets in the GI tract. They’re available alone or in combination with antacids. A major antiflatulent drug currently in use is simethicone.
Pharmacokinetics
Antiflatulents aren’t absorbed from the GI tract. They’re distributed only in the intestinal lumen and are eliminated intact in stool.
Pharmacodynamics
Antiflatulents provide defoaming action in the GI tract. By producing a film in the intestines, simethicone disperses mucus-enclosed gas pockets and helps prevent their formation.
Pharmacotherapeutics
Antiflatulents are prescribed to treat conditions in which excess gas is a problem, such as:
- functional gastric bloating
- postoperative gaseous bloating
- diverticular disease
- spastic or irritable colon
- air swallowing.
Drug interactions
Simethicone doesn’t interact significantly with other drugs and doesn’t cause known adverse reactions.
Thanks for your visit..!