Clicking moves left

Enhanced Elimination in Toxicology

Enhanced Elimination in Toxicology Extracorporeal eliminationExtracorpore [...]

Decontamination in Toxicology

Decontamination in ToxicologyorHow to Decontamination in ToxicologySingle-dose [...]

Resuscitation in Toxicology

Resuscitation in ToxicologySupportive careInitial resuscitation should be based [...]

Key investigations of Toxicology

Key investigations of Toxicology In this topic: Electrocardiography Drug conce [...]

Arterial blood gases in Toxicology

Arterial blood gases in Toxicology Arterial blood gases are an important in [...]

Clicking moves right
M O V I E
TRAVELING
Pharmacology of Disopyramide
31 Mar 2012 0 comments

Pharmacology of Disopyramide Indication For the treatment of documented ventricular arrhythmias, such as [...]

Pharmacology of Ranolazine
31 Mar 2012 0 comments

Pharmacology of Ranolazine Indication For the treatment of chronic angina. It should be used in combinati [...]

Pharmacology of Milrinone
31 Mar 2012 0 comments

Pharmacology of Milrinone Indication Indicated for the treatment of congestive heart failure. Pharma [...]

Pharmacology of Midodrine
31 Mar 2012 0 comments

Pharmacology of Midodrine   Indication For the treatment of symptomatic orthostatic hypotension [...]

Pharmacology of Dofetilide
31 Mar 2012 0 comments

Pharmacology of Dofetilide  Indication For the maintenance of normal sinus rhythm (delay in time to [...]

GALLERY
Classification of Anxiety Disorders
10 Mar 2012 0 comments

Anxiety disorders may be classified asgeneralized anxiety disorder, panic disorder, obsessive-compu [...]

Post-Traumatic Stress Disorder
10 Mar 2012 0 comments

Post-Traumatic Stress DisorderPost-traumatic stress disorder develops following a traumatic event that elicit [...]

Social Anxiety Disorder
10 Mar 2012 0 comments

Social Anxiety DisorderSocial anxiety disorder, formerly known as social phobia, is characterized by an inten [...]

TOP LINE
Classification of Anxiety Disorders
10 Mar 2012 0 comments

Anxiety disorders may be classified asgeneralized anxiety disorder, panic disorder, obsessive-compulsive disorder, social anxiety disorder, post-traumatic stress disorder. Click to view each type....

Post-Traumatic Stress Disorder
Social Anxiety Disorder
Obsessive-Compulsive Disorder
Panic Disorder
Generalized Anxiety Disorder
REVIEW
Hormonal contraceptives
25 Apr 2011 0 comments

Hormonal contraceptivesHormonal contraceptives inhibit ovulation. Contraceptives typically contain a combination of hormones. Fo...

Erectile dysfunction therapy drugs

Erectile dysfunction therapy drugsErectile dysfunction therapy drugs treat penile erectile dysfunction that results from a lack ...

Urinary tract antispasmodics

Urinary tract antispasmodicsUrinary tract antispasmodics help decrease urinary tract muscle spasms. They include darifenacin, fl...

ANALYSIS
Pharmacology of Disopyramide
31 Mar 2012 0 comments

Pharmacology of Disopyramide Indication For the treatment of documented ventricular arrhythmias, such as sustained ventricul...

Pharmacology of Ranolazine

Pharmacology of Ranolazine Indication For the treatment of chronic angina. It should be used in combination with amlodipine, ...

Pharmacology of Milrinone

Pharmacology of Milrinone Indication Indicated for the treatment of congestive heart failure. Pharmacodynamics Milri...

HIGHLIGHT
[ more from label ]
Classification of Anxiety Disorders
Post-Traumatic Stress Disorder
Social Anxiety Disorder
Obsessive-Compulsive Disorder
Latest News Updates
PERFORMANCE
Pharmacology of Disopyramide
31 Mar 2012 0 comments

Pharmacology of Disopyramide Indication For the treatment of documented ventricular arrhythmias, such as ...

Pharmacology of Ranolazine
Pharmacology of Milrinone
FEATURE
Classification of Anxiety Disorders
10 Mar 2012 0 comments

Anxiety disorders may be classified asgeneralized anxiety disorder, panic disorder, obsessive-compu...

Post-Traumatic Stress Disorder
Social Anxiety Disorder
Home » , » Lubricant laxatives
Lubricant laxatives
Tuesday, April 19, 2011 Posted by Piscean


Lubricant laxatives
Mineral oil is the main lubricant laxative currently in clinical use.
Pharmacokinetics
In its nonemulsified form, mineral oil is minimally absorbed; the emulsified form is about half absorbed. Absorbed mineral oil is distributed to the mesenteric lymph nodes, intestinal mucosa, liver, and spleen.
Metabolism and excretion
Mineral oil is metabolized by the liver and excreted in stool.
Pharmacodynamics
Mineral oil lubricates stool and the intestinal mucosa and prevents water reabsorption from the bowel lumen. The increased fluid content of stool increases peristalsis. Administration by enema also produces distention.
Pharmacotherapeutics
Mineral oil is used to treat constipation and maintain soft stool when straining is contraindicated, such as after a recent MI (to avoid Valsalva’s maneuver), eye surgery (to prevent increased pressure in the eye), or cerebral aneurysm repair (to avoid increased ICP).
 
Adverse reactions to mineral oil
Adverse reactions to mineral oil include:
  • nausea and vomiting
  • diarrhea
  • abdominal cramping.
Impacting impaction
Administered orally or by enema, this lubricant laxative is also used to treat the patient with fecal impaction.
Drug interactions
Mineral oil can interact with other drugs.
  • Mineral oil may impair the absorption of many oral drugs, including fat-soluble vitamins, hormonal contraceptives, and anti-coagulants.
  • Mineral oil may interfere with the antibacterial activity of nonabsorbable sulfonamides. To minimize drug interactions, administer mineral oil at least 2 hours before these medications

Piscean

Thanks for your visit..!

0 comments for "Lubricant laxatives"

   

Leave a reply

    March - 2025
    SMTWTFS
          1
    2345678
    9101112131415
    16171819202122
    23242526272829
    3031