Adrenaline intravenous infusion calculations
| Adrenaline intravenous infusion calculations |
| Use adrenaline 0.1% or 1:1000 solution which is 1 mg/mL [NB1] [NB2] [NB3]. Adults:The standard infusion rate for adults ranges from 1 to 20 micrograms/minute (60 to 1200 micrograms/hour). For more detail on requirements in anaphylaxis, see Table 14.15. Infusion rates should be initiated at the lower end of the above ranges but can be titrated up approximately every 3 minutes to achieve the desired effects on blood pressure and heart rate. For 50 mL bag or syringe driver, use: 3 mg/50 mL, which gives an infusion concentration of 60 micrograms/mL. Therefore run infusion at 1 to 20 mL/hour to deliver 1 to 20 micrograms/minute. For 100 mL bag, use: 6 mg/100 mL, which gives an infusion concentration of 60 micrograms/mL. Therefore run infusion at 1 to 20 mL/hour to deliver 1 to 20 micrograms/minute. For 1000 mL bag, use: 6 mg/1000 mL, which gives an infusion concentration of 6 micrograms/mL. Therefore run infusion at 10 to 200 mL per hour to deliver 1 to 20 micrograms/minute. Children:For child 30 kg or less, use: 0.3 mg/kg in 50 mL so that 1 mL/hour gives 0.1 micrograms/kg/minute. For child more than 30 kg, use: 0.15 mg/kg in 50 mL so that 1 mL/hour gives 0.05 micrograms/kg/minute. | ||
| Percent | Ratio | Concentration |
| 0.01% | 1 in 10 000 | 1 mg in 10 mL |
| 0.1% | 1 in 1000 | 1 mg/mL (most commonly available) |
| 1% | 1 in 100 | 10 mg/mL |
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