Pharmacology Notes

A protocol for full blood count monitoring (at least every 2 weeks) should be established before initiating therapy. Patients with borderline cell counts may need more frequent monitoring.Urine analysis should be performed monthly, and patients advised to report dysuria. Cystoscopy should be performed if cystitis is suspected either because of symptoms, or asymptomatic abnormality on urine analysis. If cystitis is confirmed, it is a contraindication to further use of cyclophosphamide.