Pharmacology Notes

Topical and transdermal formulations are widely used, and are useful in the treatment of local musculoskeletal disorders. Some NSAIDs that are used systemically are available for topical use  They are gels that are usually used for muscular aches and pains. They are a safer alternative to oral NSAIDs, are usually absorbed only in small amounts, and may be somewhat less effective. However, they can still cause gastrointestinal haemorrhage. Methyl salicylate and benzydamine, NSAIDs that are not used systemically, are available as topical formulations.