Antimetabolite drugs
Antimetabolite drugs
Because antimetabolite drugs structurally resemble DNA base pairs, they can become involved in processes associated with DNA base pairs’that is, the synthesis of nucleic acids and proteins.
Getting specific
Antimetabolites differ sufficiently from DNA base pairs in how they interfere with this synthesis. Because the antimetabolites are cell cycle’specific and primarily affect cells that actively synthesize DNA, they’re referred to as S phase’specific. Normal cells that are reproducing actively, as well as the cancer cells, are affected by the antimetabolites.
Thanks for your visit..!